A system and method is disclosed for initializing PCI devices in a computer system or information handling system. Upon initialization of the system, each operating system instance of the system attempts to access a PCI bridge device. The first operating system to access the bridge device is granted ownership of the bridge device and the authority to initialize each PCI device coupled to the bridge device. The bridge device assigns each operating system to at least one context included in at least one of the PCI devices. After each of the PCI devices has been initialized, a configuration event is issued with respect to each operating system instance and each assigned PCI device, thereby causing each operating system to recognize each PCI device assigned to each respective operating system instance.