A bed frame or other structural construction having a locking mechanism to allow two structural members to be affixed and locked together. A first structural member sits atop of the second structural member and has a pair of posts that interfit into a pair of holes formed in the second structural member. The locking mechanism is located at an end of the first structural member and includes a slide that is movable along the longitudinal axis of the first structural member to slide between a retracted, unlocked position and an extended, locked position where the slide contacts the lower surface of the second structural member to sandwich the second structural member between the first structural member and the slide to block the structural members from moving with respect to each to withdraw the posts from the holes, thereby locking the first and second structural members together.