Invention Grant
- Patent Title: Rapid-heating drug delivery article and method of use
- Patent Title (中): 快速加热药物输送物品及其使用方法
-
Application No.: US10633876Application Date: 2003-08-04
-
Publication No.: US07645442B2Publication Date: 2010-01-12
- Inventor: Ron L. Hale , Peter M. Lloyd , Amy Lu , Daniel J. Myers , Reynaldo J. Quintana , Joshua D. Rabinowitz , Dennis W. Solas , Soonho Song , Curtis Tom , Martin J. Wensley
- Applicant: Ron L. Hale , Peter M. Lloyd , Amy Lu , Daniel J. Myers , Reynaldo J. Quintana , Joshua D. Rabinowitz , Dennis W. Solas , Soonho Song , Curtis Tom , Martin J. Wensley
- Applicant Address: US CA Mountain View
- Assignee: Alexza Pharmaceuticals, Inc.
- Current Assignee: Alexza Pharmaceuticals, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Swanson & Bratschun, L.L.C.
- Main IPC: A61K9/12
- IPC: A61K9/12 ; A61K9/14 ; A61M15/00

Abstract:
A device, method, and system for producing a condensation aerosol are disclosed. The device includes a chamber having an upstream opening and a downstream opening which allow gas to flow through the chamber, and a heat-conductive substrate located at a position between the upstream and downstream openings. Formed on the substrate is a drug composition film containing a therapeutically effective dose of a drug when the drug is administered in aerosol form. A heat source in the device is operable to supply heat to the substrate to produce a substrate temperature greater than 300° C., and to substantially volatilize the drug composition film from the substrate in a period of 2 seconds or less. The device produces an aerosol containing less than about 10% by weight drug composition degradation products and at least 50% of the drug composition of said film.
Public/Granted literature
- US20070028916A1 Rapid-heating drug delivery article and method of use Public/Granted day:2007-02-08
Information query