Invention Grant
- Patent Title: Alpha-enolase specific antibody and method of use
- Patent Title (中): α-烯醇酶特异性抗体及其使用方法
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Application No.: US11648132Application Date: 2006-12-29
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Publication No.: US07645453B2Publication Date: 2010-01-12
- Inventor: Neng-Yao Shih , Gee-Chen Chang , Ko-Jiunn Liu
- Applicant: Neng-Yao Shih , Gee-Chen Chang , Ko-Jiunn Liu
- Applicant Address: TW Miaolo County
- Assignee: National Health Research Institutes
- Current Assignee: National Health Research Institutes
- Current Assignee Address: TW Miaolo County
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- Main IPC: A61K39/00
- IPC: A61K39/00

Abstract:
This invention relates to a method of monitoring cancer development by determining the abundance of alpha-enolase protein wherein increased abundance is an indication of the severity of cancer. In another embodiment, the invention relates to a method of detecting cancer malignancy by determining the abundance of alpha-enolase antibodies in a sample wherein low levels of such antibodies indicates the malignancy of cancer. Also provided is a method of suppressing tumor growth by inducing the anti-ENO1 immune response.
Public/Granted literature
- US20070172487A1 Alpha-enolase specific antibody and method of use Public/Granted day:2007-07-26
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