Invention Grant
- Patent Title: Heat-resistant nitrile hydratase
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Application No.: US11569529Application Date: 2005-05-26
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Publication No.: US07645605B2Publication Date: 2010-01-12
- Inventor: Fumiaki Watanabe , Dai Ujihara , Miki Sakai , Fujio Yu , Tetsuji Nakamura
- Applicant: Fumiaki Watanabe , Dai Ujihara , Miki Sakai , Fujio Yu , Tetsuji Nakamura
- Applicant Address: JP Tokyo
- Assignee: Mitsubishi Rayon Co., Ltd
- Current Assignee: Mitsubishi Rayon Co., Ltd
- Current Assignee Address: JP Tokyo
- Agency: Darby & Darby, P.C
- Priority: JP2004-156593 20040526; JP2004-237888 20040818
- International Application: PCT/JP2005/010107 WO 20050526
- International Announcement: WO2005/116206 WO 20051208
- Main IPC: C12N9/88
- IPC: C12N9/88 ; C12N9/00 ; C12N1/20 ; C12N15/00 ; C07H21/04

Abstract:
The present invention provides: a protein having an improved nitrile hydratase activity, whereby heat resistance has been improved when compared with a wild-type nitrile hydratase activity, wherein the amino acid sequence of a nitrile hydratase is modified; a gene DNA encoding the above protein; a recombinant vector having the above gene DNA; a transformant or transductant having the above recombinant vector; a nitrile hydratase collected from a culture of the above transformant or transductant, and a production method thereof; and a method for producing an amide compound.
Public/Granted literature
- US20070231868A1 Nitrile Hydratase Public/Granted day:2007-10-04
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