Invention Grant
US07645752B2 Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors
失效
磺酰基取代的1H-吲哚作为5-羟色胺受体的配体
- Patent Title: Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors
- Patent Title (中): 磺酰基取代的1H-吲哚作为5-羟色胺受体的配体
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Application No.: US11622649Application Date: 2007-01-12
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Publication No.: US07645752B2Publication Date: 2010-01-12
- Inventor: Robert E. McDevitt , Yanfang Li , Albert J. Robichaud , Gavin D. Heffernan , Richard D. Coghlan , Ronald C. Bernotas
- Applicant: Robert E. McDevitt , Yanfang Li , Albert J. Robichaud , Gavin D. Heffernan , Richard D. Coghlan , Ronald C. Bernotas
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent Doina G. Ene; Scott Larsen
- Main IPC: A61K31/404
- IPC: A61K31/404 ; A61K31/454 ; A61K31/55 ; A61K31/10 ; C07D403/02 ; C07D209/30 ; C07C317/32
Abstract:
The present invention is directed to compounds of Formula I: which are modulators of the 5-hydroxtryptamine-6 and 5-hydroxytryptamine-2A receptors and which are inhibitors of norepinephrine reuptake. The compounds of the invention, and pharmaceutical composition thereof, are useful in the treatment of disorders related to or associated with the 5-hydroxytryptamine-6 and 5-hydroxtryptamine-2A receptors or with norepinephrine reuptake inhibition.
Public/Granted literature
- US20070203120A1 Sulfonyl Substituted 1H-Indoles as Ligands for the 5-Hydroxytryptamine Receptors Public/Granted day:2007-08-30
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