Invention Grant
- Patent Title: Thiazoles as inhibitors of 11β-hydroxysteroid dehydrogenase
- Patent Title (中): 噻唑作为11β-羟基类固醇脱氢酶的抑制剂
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Application No.: US11650645Application Date: 2007-01-08
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Publication No.: US07645773B2Publication Date: 2010-01-12
- Inventor: Paul Gillespie , Robert Alan Goodnow, Jr. , Agnieszka Kowalczyk , Kang Le , Qiang Zhang
- Applicant: Paul Gillespie , Robert Alan Goodnow, Jr. , Agnieszka Kowalczyk , Kang Le , Qiang Zhang
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61K31/427 ; C07D403/02 ; C07D215/00 ; C07D277/20

Abstract:
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
Public/Granted literature
- US20070167622A1 Thiazoles as inhibitors of 11B-hydroxysteroid dehydrogenase Public/Granted day:2007-07-19
Information query
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