Invention Grant
- Patent Title: Methods of indentifying modulators of the FGF receptor
- Patent Title (中): 识别FGF受体调节剂的方法
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Application No.: US11183567Application Date: 2005-07-18
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Publication No.: US07645857B2Publication Date: 2010-01-12
- Inventor: Ming-Ming Zhou , Mitchell Goldfarb
- Applicant: Ming-Ming Zhou , Mitchell Goldfarb
- Applicant Address: US NY New York
- Assignee: Mount Sinai School of Medicine
- Current Assignee: Mount Sinai School of Medicine
- Current Assignee Address: US NY New York
- Agency: Klauber & Jackson, LLC
- Main IPC: C07K9/00
- IPC: C07K9/00 ; C07K4/12 ; C07K14/435
Abstract:
The present invention provides fragments of SNT and FGFR which can form a binding complex that is amenable to structural determinations by NMR spectroscopy. The three-dimensional structural data is also included as part of the invention. In addition, the present invention provides methodology for related structure based rational drug design using the three-dimensional data. Nucleotide and amino acid sequences of the fragments are also provided.
Public/Granted literature
- US20060019296A1 Methods of indentifying modulators of the FGF receptor Public/Granted day:2006-01-26
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