Invention Grant
US07645870B2 siRNA targeting proteasome 26S subunit, non-ATPase, 10 (Gankyrin or PSMD10)
有权
siRNA靶向蛋白酶体26S亚基，非ATPase，10（Gankyrin或PSMD10）
- Patent Title: siRNA targeting proteasome 26S subunit, non-ATPase, 10 (Gankyrin or PSMD10)
- Patent Title (中): siRNA靶向蛋白酶体26S亚基，非ATPase，10（Gankyrin或PSMD10）
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Application No.: US11811423Application Date: 2007-06-08
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Publication No.: US07645870B2Publication Date: 2010-01-12
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Kalow & Springut, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A01N43/04 ; A61K31/70
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to PSMD10.
Public/Granted literature
- US20080071075A1 siRNA targeting proteasome 26S subunit, non-ATPase, 10 (Gankyrin or PSMD10) Public/Granted day:2008-03-20
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