A control circuit of a DC-DC converter is provided. A mode selection section selects an Active Clamp Forward (ACF) or a Logic Link Control (LLC) mode. A soft start section generates a soft start signal in the ACF and LLC modes. A PWM comparison section compares a current detection signal with a feedback signal, a feedback reference signal and the soft start signal in the ACF mode, and generates a PWM signal based on a comparison result. A selection section selects the PWM signal of the PWM comparison section in the ACF mode. A clock generation section generates a clock signal having a fixed frequency in the ACF mode, and generates a clock signal having a frequency based on an operating current and the soft start signal in the LLC mode. A latch section maintains the PWM signal in response to the clock signal in the ACF mode and maintains the clock signal in the LLC mode.