Invention Grant
- Patent Title: High throughput directed evolution by rational mutagenesis
- Patent Title (中): 通过合理诱变进行高通量定向进化
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Application No.: US10022249Application Date: 2001-12-17
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Publication No.: US07647184B2Publication Date: 2010-01-12
- Inventor: Manuel Vega , Lila Drittanti
- Applicant: Manuel Vega , Lila Drittanti
- Applicant Address: KR Daejeon
- Assignee: Hanall Pharmaceuticals, Co. Ltd
- Current Assignee: Hanall Pharmaceuticals, Co. Ltd
- Current Assignee Address: KR Daejeon
- Agency: K & L Gates LLP
- Agent Stephanie Seidman
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
Processes and systems for the high throughput directed evolution of peptides and proteins, particularly those that act in complex biological settings, are provided. The proteins and peptides include, but are not limited to, intracellular proteins, messenger/signaling/hormone proteins and viral proteins. Also provided is a rational method for generating protein variants and also a method for titering viruses.
Public/Granted literature
- US20030134351A1 High throughput directed evolution by rational mutagenesis Public/Granted day:2003-07-17
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