Invention Grant
- Patent Title: 19-nor-vitamin D analogs with 3,2-dihydrofuran ring
- Patent Title (中): 19-维生素D类似物与3,2二氢呋喃环
-
Application No.: US12171108Application Date: 2008-07-10
-
Publication No.: US07648974B1Publication Date: 2010-01-19
- Inventor: Hector F. DeLuca , Agnieszka Glebocka , Katarzyna Sokolowska , Rafal R. Sicinski , Lori A. Plum , Margaret Clagett-Dame
- Applicant: Hector F. DeLuca , Agnieszka Glebocka , Katarzyna Sokolowska , Rafal R. Sicinski , Lori A. Plum , Margaret Clagett-Dame
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Andrus, Sceales, Starke & Sawall, LLP
- Main IPC: A61K31/59
- IPC: A61K31/59 ; C07C401/00 ; C07D317/00
Abstract:
19-nor-vitamin D analogs having an additional dihydrofuran ring connecting the 3β-oxygen and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit selective in vitro and in vivo activities, making them therapeutic agents for the treatment or prophylaxis of autoimmune diseases, some types of cancers, metabolic bone diseases, osteomalacia, osteopenia, secondary hyperparathyroidism, psoriasis, or other skin diseases.
Public/Granted literature
- US20100009945A1 19-NOR-VITAMIN D ANALOGS WITH 3,2-DIHYDROFURAN RING Public/Granted day:2010-01-14
Information query
