Invention Grant
- Patent Title: 39-desmethoxy derivatives of rapamycin
- Patent Title (中): 雷帕霉素的39-去甲氧基衍生物
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Application No.: US11908250Application Date: 2006-03-10
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Publication No.: US07648996B2Publication Date: 2010-01-19
- Inventor: Christoph Hendrik Beckmann , Steven James Moss , Rose Mary Sheridan , Mingqiang Zhang , Barrie Wilkinson
- Applicant: Christoph Hendrik Beckmann , Steven James Moss , Rose Mary Sheridan , Mingqiang Zhang , Barrie Wilkinson
- Applicant Address: GB
- Assignee: Biotica Technology Limited
- Current Assignee: Biotica Technology Limited
- Current Assignee Address: GB
- Agent Michael J. Herman; Paul Carango
- Priority: GB0504994.5 20050311
- International Application: PCT/GB2006/000853 WO 20060310
- International Announcement: WO2006/095185 WO 20060914
- Main IPC: C07D498/18
- IPC: C07D498/18 ; A61K31/436
Abstract:
The present invention relates to novel 39-desmethoxyrapamycin derivatives, methods for their production, and uses thereof. In a further aspect the present invention provides for the use of these 39-desmethoxyrapamycin derivatives in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.
Public/Granted literature
- US20080188511A1 39-Desmethoxy Derivatives of Rapamycin Public/Granted day:2008-08-07
Information query
