Invention Grant
US07649015B2 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds
有权
HIV蛋白酶抑制剂化合物的膦酸酯类似物的细胞积累
- Patent Title: Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds
- Patent Title (中): HIV蛋白酶抑制剂化合物的膦酸酯类似物的细胞积累
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Application No.: US10423496Application Date: 2003-04-25
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Publication No.: US07649015B2Publication Date: 2010-01-19
- Inventor: Murty N. Arimili , Xiaowu Chen , Maria Fardis , Gong-Xin He , Haolun Jin , Choung U. Kim , William A. Lee , Kuei-Ying Lin , Hongtao Liu , Richard L. Mackman , Michael L. Mitchell , Hyung-Jung Pyun , Mark Sparacino , Sundaramoorthi Swaminathan , Jianying Wang , Matthew A. Williams , Lianhong Xu , Zheng-Yu Yang , Richard H. Yu , Jiancun Zhang , Lijun Zhang
- Applicant: Murty N. Arimili , Xiaowu Chen , Maria Fardis , Gong-Xin He , Haolun Jin , Choung U. Kim , William A. Lee , Kuei-Ying Lin , Hongtao Liu , Richard L. Mackman , Michael L. Mitchell , Hyung-Jung Pyun , Mark Sparacino , Sundaramoorthi Swaminathan , Jianying Wang , Matthew A. Williams , Lianhong Xu , Zheng-Yu Yang , Richard H. Yu , Jiancun Zhang , Lijun Zhang
- Applicant Address: US CA Palo Alto
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Palo Alto
- Agency: Gilead Sciences, Inc.
- Agent Max D. Hensley; Cynthia H. Zhang
- Main IPC: A61K31/343
- IPC: A61K31/343 ; C07F9/28
Abstract:
Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.
Public/Granted literature
- US20050209197A1 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds Public/Granted day:2005-09-22
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