Invention Grant
US07649018B2 Mono- and di-phosphates of 3-(3-fluoro-4-hydroxy-phenyl)-7-hydroxy-naphthalene-1-carbonitrile
失效
3-（3-氟-4-羟基 - 苯基）-7-羟基 - 萘-1-甲腈的单磷酸酯和二磷酸酯
- Patent Title: Mono- and di-phosphates of 3-(3-fluoro-4-hydroxy-phenyl)-7-hydroxy-naphthalene-1-carbonitrile
- Patent Title (中): 3-（3-氟-4-羟基 - 苯基）-7-羟基 - 萘-1-甲腈的单磷酸酯和二磷酸酯
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Application No.: US12034052Application Date: 2008-02-20
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Publication No.: US07649018B2Publication Date: 2010-01-19
- Inventor: Mahdi B. Fawzi , Parimal R. Desai , Tianmin Zhu
- Applicant: Mahdi B. Fawzi , Parimal R. Desai , Tianmin Zhu
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agency: Pepper Hamilton LLP
- Main IPC: C07C255/52
- IPC: C07C255/52
Abstract:
Compounds of formula II wherein each R1 and R2 is independently selected from H and —P(O)(R3)(R4), provided that at least one of R1 and R2 is —P(O)(R3)(R4); each R3 and R4 is independently selected from the group consisting of H, —OH, C1-C6 alkyl, and C1-C6 alkoxy; or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions comprising a compound of formula II, and methods of administering such compounds and compositions.
Public/Granted literature
- US20080214507A1 MONO-AND-DI-PHOSPHATES OF 3-(3-FLUORO-4-HYDROXY-PHENYL)-7-HYDROXY-NAPHTHALENE-1-CARBONITRILE Public/Granted day:2008-09-04
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