Invention Grant
- Patent Title: Hepatocyte growth factor (HGF) binding antibody
- Patent Title (中): 肝细胞生长因子（HGF）结合抗体
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Application No.: US11757059Application Date: 2007-06-01
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Publication No.: US07649083B2Publication Date: 2010-01-19
- Inventor: William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
- Applicant: William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
- Applicant Address: US MA Cambridge US CA Berkeley
- Assignee: AVEO Pharmaceuticals, Inc.,XOMA Technology Ltd.
- Current Assignee: AVEO Pharmaceuticals, Inc.,XOMA Technology Ltd.
- Current Assignee Address: US MA Cambridge US CA Berkeley
- Agency: Goodwin Procter LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/24
Abstract:
The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Public/Granted literature
- US20080108565A1 HEPATOCYTE GROWTH FACTOR (HGF) BINDING PROTEINS Public/Granted day:2008-05-08
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