Invention Grant
US07649096B2 Process for the preparation of a crystalline form of (S)-N [[3-(3-fluoro-4(4-morpholinyl) phenyl]-2-oxo-5-oxazolidinyl] methyl] acetamide
有权
（S）-N [[3-（3-氟-4（4-吗啉基）苯基] -2-氧代-5-恶唑烷基]甲基]乙酰胺的结晶形式的制备方法
![Process for the preparation of a crystalline form of (S)-N [[3-(3-fluoro-4(4-morpholinyl) phenyl]-2-oxo-5-oxazolidinyl] methyl] acetamide](/docs/US/2010-01-19/US07649096B2/abs.jpg.600x600.jpg)
- Patent Title: Process for the preparation of a crystalline form of (S)-N [[3-(3-fluoro-4(4-morpholinyl) phenyl]-2-oxo-5-oxazolidinyl] methyl] acetamide
- Patent Title (中): （S）-N [[3-（3-氟-4（4-吗啉基）苯基] -2-氧代-5-恶唑烷基]甲基]乙酰胺的结晶形式的制备方法
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Application No.: US11487766Application Date: 2006-07-17
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Publication No.: US07649096B2Publication Date: 2010-01-19
- Inventor: Bobba Venkata Siva Kumar , Pravin Bhalchandra Kulkarni , Girish Bansilal Patel , Nitin Sharad Chandra Pradhan
- Applicant: Bobba Venkata Siva Kumar , Pravin Bhalchandra Kulkarni , Girish Bansilal Patel , Nitin Sharad Chandra Pradhan
- Applicant Address: IN Mumbai
- Assignee: Glenmark Pharmaceuticals Limited
- Current Assignee: Glenmark Pharmaceuticals Limited
- Current Assignee Address: IN Mumbai
- Agency: M. Carmen & Associates, PLLC
- Priority: IN853/2005 20050715
- Main IPC: C07D413/10
- IPC: C07D413/10 ; C07D413/02
![Process for the preparation of a crystalline form of (S)-N [[3-(3-fluoro-4(4-morpholinyl) phenyl]-2-oxo-5-oxazolidinyl] methyl] acetamide](/abs-image/US/2010/01/19/US07649096B2/abs.jpg.150x150.jpg)
Abstract:
A process for preparing a crystalline form of linezolid is provided comprising (a) providing a solution comprising linezolid in an organic solvent having a boiling point of less than or equal to about 150° C.; (b) adding an anti-solvent having a boiling point greater than or equal to about 50° C. to the solution; and (c) recovering the crystalline form of linezolid.
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