Invention Grant
- Patent Title: Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
- Patent Title (中): 用于治疗代谢紊乱的化合物,药物组合物和方法
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Application No.: US11067377Application Date: 2005-02-25
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Publication No.: US07649110B2Publication Date: 2010-01-19
- Inventor: Michelle Akerman , Jonathan Houze , Daniel C. H. Lin , Jinqian Liu , Jiwen Liu , Jian Luo , Zhihua Ma , Julio C. Medina , Wei Qiu , Jeffrey D. Reagan , Rajiv Sharma , Michael J. Schmitt , Stephen J. Shuttleworth , Ying Sun , Yingcai Wang , Jian Zhang , Liusheng Zhu
- Applicant: Michelle Akerman , Jonathan Houze , Daniel C. H. Lin , Jinqian Liu , Jiwen Liu , Jian Luo , Zhihua Ma , Julio C. Medina , Wei Qiu , Jeffrey D. Reagan , Rajiv Sharma , Michael J. Schmitt , Stephen J. Shuttleworth , Ying Sun , Yingcai Wang , Jian Zhang , Liusheng Zhu
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard Friedrichsen
- Main IPC: C07C59/40
- IPC: C07C59/40 ; C07C65/03

Abstract:
The present invention provides compounds useful, for example, for modulating insulin levels in a subject and that have the general formula Q—L1—P—L2—M—X—L3—A wherein the definitions of the variables Q, L1, P, L2, M, X, L3 and A are provided herein. The present invention also provides compositions and methods for use of the compounds, for instance, for treatment of type II diabetes.
Public/Granted literature
- US20060004012A1 Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders Public/Granted day:2006-01-05
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