Invention Grant
US07650243B2 Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
失效
细胞因子的合理演化为更高的稳定性，细胞因子和编码核酸分子
- Patent Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
- Patent Title (中): 细胞因子的合理演化为更高的稳定性，细胞因子和编码核酸分子
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Application No.: US11707014Application Date: 2007-02-14
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Publication No.: US07650243B2Publication Date: 2010-01-19
- Inventor: Rene Gantier , Manuel Vega , Lila Drittanti , Thierry Guyon
- Applicant: Rene Gantier , Manuel Vega , Lila Drittanti , Thierry Guyon
- Applicant Address: KR Daejeon
- Assignee: Hanall Pharmaceutical Co., Ltd.
- Current Assignee: Hanall Pharmaceutical Co., Ltd.
- Current Assignee Address: KR Daejeon
- Agency: K & L Gates LLP
- Agent Stephanie Seidman
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.
Public/Granted literature
- US20070224665A1 Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules Public/Granted day:2007-09-27
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