Invention Grant
- Patent Title: Method for screening agents capable of treating obesity
- Patent Title (中): 筛选能够治疗肥胖症的药剂的方法
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Application No.: US10416444Application Date: 2001-11-08
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Publication No.: US07651844B2Publication Date: 2010-01-26
- Inventor: Sophie Tartare-Deckert , Emmanuel Van Obberghen
- Applicant: Sophie Tartare-Deckert , Emmanuel Van Obberghen
- Applicant Address: FR Lyons FR Paris
- Assignee: Merck Sante,Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee: Merck Sante,Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee Address: FR Lyons FR Paris
- Agency: Young & Thompson
- Priority: FR0014487 20001110
- International Application: PCT/FR01/03473 WO 20011108
- International Announcement: WO02/38807 WO 20020516
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A01N1/02 ; C12Q1/68
Abstract:
The invention concerns a method for screening agents capable of treating, by way of prevention or cure, obesity or one of the disorders associated with obesity by modulating the expression of the SPARC protein or of its activity. The invention also concerns a method for diagnosing obesity or one of the disorders associated with obesity by monitoring the expression rate of the SPARC protein or its activity. The invention further concerns a composition comprising an agent modulating the expression of the SPARC protein or its activity. The invention finally concerns the use of any agent modulating the expression of the SPARC protein or its activity for preparing a pharmaceutical composition for treating, by way of prevention or cure, obesity or one of the disorders associated with obesity.
Public/Granted literature
- US20040049799A1 Method for screening agents capable of treating obesity Public/Granted day:2004-03-11
Information query
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