Invention Grant
US07652007B2 Nitrogen-substituted hexahydropyrazino[1,2-A]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments
有权
氮取代六氢吡嗪并[1,2-A]嘧啶-4,7-二酮衍生物,其制备方法及其作为药物的用途
- Patent Title: Nitrogen-substituted hexahydropyrazino[1,2-A]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments
- Patent Title (中): 氮取代六氢吡嗪并[1,2-A]嘧啶-4,7-二酮衍生物,其制备方法及其作为药物的用途
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Application No.: US10779439Application Date: 2004-02-13
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Publication No.: US07652007B2Publication Date: 2010-01-26
- Inventor: Stefanie Flohr , Siegfried Stengelin , Matthias Gossel , Thomas Klabunde , Petra Stahl , Pavel Safar , James Spoonamore , Martin Smrcina , Joseph Klein , Gregory Merriman , Brian Whiteley , Carolina Lanter , Kenneth Bordeau , Zhaoxia Yang
- Applicant: Stefanie Flohr , Siegfried Stengelin , Matthias Gossel , Thomas Klabunde , Petra Stahl , Pavel Safar , James Spoonamore , Martin Smrcina , Joseph Klein , Gregory Merriman , Brian Whiteley , Carolina Lanter , Kenneth Bordeau , Zhaoxia Yang
- Applicant Address: DE Frankfurt am Main
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agent Barbara E. Kurys
- Priority: DE10305885 20030213; DE10349671 20031024
- Main IPC: C07D487/00
- IPC: C07D487/00 ; A61K31/495 ; A01N43/60
![Nitrogen-substituted hexahydropyrazino[1,2-A]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments](/abs-image/US/2010/01/26/US07652007B2/abs.jpg.150x150.jpg)
Abstract:
Nitrogen-substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives, processes for the preparation and their use as medicamentsThe invention relates to substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof.Compounds of the formula I in which the radicals have the stated meanings, and the physiologically tolerated salts thereof and processes for preparing them are described. The compounds are suitable for example as anorectic agents.
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