Invention Grant
- Patent Title: Methods of lowering lipid levels in a mammal
- Patent Title (中): 降低哺乳动物血脂水平的方法
-
Application No.: US11948574Application Date: 2007-11-30
-
Publication No.: US07652037B2Publication Date: 2010-01-26
- Inventor: Samuel Rahbar , James L. Figarola
- Applicant: Samuel Rahbar , James L. Figarola
- Applicant Address: US CA Duarte
- Assignee: City Of Hope
- Current Assignee: City Of Hope
- Current Assignee Address: US CA Duarte
- Agency: Rothwell, Figg, Ernst & Manbeck p.c.
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61K31/195
Abstract:
This invention relates to methods for lowering lipid levels in mammals using compounds that inhibit advanced glycation endproducts (AGEs), LR-9, LR-74 and LR-90. These compounds, which inhibit non-enzymatic protein glycation, also inhibit the formation of advanced lipoxidation endproducts (ALES) on target proteins by trapping intermediates in glycoxidation and lopoxidation and inhibiting oxidation reactions important in the formation of AGEs and ALEs.
Public/Granted literature
- US20080200502A1 METHODS OF LOWERING LIPID LEVELS IN A MAMMAL Public/Granted day:2008-08-21
Information query
