Invention Grant
US07652046B2 Substituted thienopyrrole carboxylic acid amides, pyrrolothiazole carboxylic acid amides, and related analogs as inhibitors of casein kinase I
有权
取代的噻吩并吡咯羧酸酰胺，吡咯并噻唑羧酸酰胺和相关类似物作为酪蛋白激酶I的抑制剂
- Patent Title: Substituted thienopyrrole carboxylic acid amides, pyrrolothiazole carboxylic acid amides, and related analogs as inhibitors of casein kinase I
- Patent Title (中): 取代的噻吩并吡咯羧酸酰胺，吡咯并噻唑羧酸酰胺和相关类似物作为酪蛋白激酶I的抑制剂
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Application No.: US12125450Application Date: 2008-05-22
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Publication No.: US07652046B2Publication Date: 2010-01-26
- Inventor: David Marc Fink , Yulin Chiang , Nicola Dawn Collar
- Applicant: David Marc Fink , Yulin Chiang , Nicola Dawn Collar
- Applicant Address: US NJ Bridgewater
- Assignee: Aventis Pharmaceuticals Inc.
- Current Assignee: Aventis Pharmaceuticals Inc.
- Current Assignee Address: US NJ Bridgewater
- Agent Balaram Gupta
- Main IPC: A61K31/429
- IPC: A61K31/429 ; A61K31/407
Abstract:
The present invention comprises methods for the treatment of central nervous system diseases and disorders including mood disorders and sleep disorders through the administration of compounds of formula (I) and formula (II) which are useful as inhibitors of human casein kinase Iε. Pharmaceutical compositions comprising compounds of formula (I) or formula (II) as well as methods for their preparation are also disclosed and claimed.
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