Invention Grant
- Patent Title: Phenylamino isothiazole carboxamidines as MEK inhibitors
- Patent Title (中): 苯基氨基异噻唑甲酰胺作为MEK抑制剂
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Application No.: US12171844Application Date: 2008-07-11
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Publication No.: US07652047B2Publication Date: 2010-01-26
- Inventor: Hassan El Abdellaoui , Robert Tam , Huanming Chen , Varaprasad Chamakura , Dinesh Barawkar , Andreas Maderna , Zhi Hong , Stanley Lang
- Applicant: Hassan El Abdellaoui , Robert Tam , Huanming Chen , Varaprasad Chamakura , Dinesh Barawkar , Andreas Maderna , Zhi Hong , Stanley Lang
- Applicant Address: US CA San Diego
- Assignee: Ardea Biosciences, Inc.
- Current Assignee: Ardea Biosciences, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Millen, White, Zelano & Branigan, P.C.
- Main IPC: A61K31/425
- IPC: A61K31/425 ; A61K31/427 ; A61K31/5377 ; A61K31/506 ; A61K31/4439 ; A61K31/496
Abstract:
The invention concerns compounds which inhibit MEK and which have activity as anti-neoplastic agents. These compounds include N-substituted-3-hydroxy-5-arylamino-isothiazole-4-carboxamidines. Also included are the tautomeric isothiazol-3(2H)-ones.
Public/Granted literature
- US20080306063A1 PHENYLAMINO ISOTHIAZOLE CARBOXAMIDINES AS MEK INHIBITORS Public/Granted day:2008-12-11
Information query
