Invention Grant
- Patent Title: Methods for converting quinolone esters into quinolone amides
- Patent Title (中): 将喹诺酮酯转化成喹诺酮酰胺的方法
-
Application No.: US11149007Application Date: 2005-06-09
-
Publication No.: US07652134B2Publication Date: 2010-01-26
- Inventor: Jeffrey P. Whitten , Fabrice Pierre , Collin Regan , Michael Schwaebe , George Petros Yiannikouros , Michael Jung
- Applicant: Jeffrey P. Whitten , Fabrice Pierre , Collin Regan , Michael Schwaebe , George Petros Yiannikouros , Michael Jung
- Applicant Address: US CA San Diego
- Assignee: Cylene Pharmaceuticals, Inc.
- Current Assignee: Cylene Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Morrison & Foerster LLP
- Main IPC: C07D413/14
- IPC: C07D413/14 ; C07D401/14
Abstract:
The present invention relates to methods of preparing compounds having formula (1), (2), (5), and ((6A)-(6D)) comprising contacting the corresponding ester, an amine with formula NHR1R2, and a Lewis acid having formula MLn, wherein L is a halogen atom or an organic radical, n is 3-5, and M is a group III elemental atom, a group IV elemental atom, As, Sb, V or Fe, wherein A, B, V, X, Z, W, R1, R2, R5, Z1, Z2, Z3, Z4, Z5, Z6, Z7, and Z8 are substituents. Z4, Z5, Z6, Z7, and Z8 are substituents.
Public/Granted literature
- US20060063761A1 Novel benzothiazole compounds and methods of use thereof Public/Granted day:2006-03-23
Information query
