Invention Grant
- Patent Title: Neural stem cells and use thereof for brain tumor therapy
- Patent Title (中): 神经干细胞及其在脑肿瘤治疗中的应用
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Application No.: US11546726Application Date: 2006-10-12
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Publication No.: US07655224B2Publication Date: 2010-02-02
- Inventor: Evan Y. Snyder , Xandra O. Breakefield , Karen S. Aboody , Ulrich Herrlinger , William P. Lynch
- Applicant: Evan Y. Snyder , Xandra O. Breakefield , Karen S. Aboody , Ulrich Herrlinger , William P. Lynch
- Applicant Address: US MA Boston US MA Boston US OH Rootstown
- Assignee: Children's Medical Center Corp.,The General Hospital Corp.,Northeastern Ohio Universities COM
- Current Assignee: Children's Medical Center Corp.,The General Hospital Corp.,Northeastern Ohio Universities COM
- Current Assignee Address: US MA Boston US MA Boston US OH Rootstown
- Agency: Nixon Peabody LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/63 ; C12N5/08 ; A61K31/70
Abstract:
The present invention is based upon a surprising finding that stem cells, more particularly neural stem cells, can migrate throughout a brain tumor and track metastatic brain tumor cells. The invention provides a method for treating brain tumors by administering genetically engineered neural stem cells in an individual affected by brain tumors. The invention also provides a method of preparing genetically engineered neural stem cells and a composition comprising genetically engineered neural stem cells in a pharmaceutically acceptable carrier.
Public/Granted literature
- US20070031391A1 Neural stem cells and use thereof for brain tumor therapy Public/Granted day:2007-02-08
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