Invention Grant
US07655240B2 Vaccine composition comprising an immunoadjuvant compound consisting of a Rho GTPase family activator
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疫苗组合物,其包含由Rho GTP酶家族激活剂组成的免疫佐剂化合物
- Patent Title: Vaccine composition comprising an immunoadjuvant compound consisting of a Rho GTPase family activator
- Patent Title (中): 疫苗组合物,其包含由Rho GTP酶家族激活剂组成的免疫佐剂化合物
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Application No.: US10589505Application Date: 2005-02-25
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Publication No.: US07655240B2Publication Date: 2010-02-02
- Inventor: Emmanuel Lemichez , Cécil Czerkinsky , Fabienne Anjuere , Patrice Boquet , Patrick Munro , Gilles Flatau
- Applicant: Emmanuel Lemichez , Cécil Czerkinsky , Fabienne Anjuere , Patrice Boquet , Patrick Munro , Gilles Flatau
- Applicant Address: FR Paris
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee Address: FR Paris
- Agency: Young & Thompson
- Priority: EP04300100 20040226
- International Application: PCT/EP2005/002105 WO 20050225
- International Announcement: WO2005/082408 WO 20050909
- Main IPC: A61K39/02
- IPC: A61K39/02

Abstract:
This invention is based on the experimental finding that activators of Rho GTPases, namely the cytotoxic necrotizing factor 1 (CNF1), and DNT bear immunostimulatory properties towards the systemic response to orally administered ovalbumine. This invention concerns a vaccine composition including an immunoadjuvant compound, wherein the immunoadjuvant compound consists of a Rho GTPase activator.
Public/Granted literature
- US20070172491A1 Vaccine composition comprising an immunoadjuvant compound consisting of a rho gtpase family activator Public/Granted day:2007-07-26
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