Supplement preparation including (a), a first active component in form of biologically accessible silver, (b), a second active component in form of a material obtained from cartilage, and any conventional accessory agents or additives and the use of the first and the second active components with any additional active components and/or conventional accessory agent or additives for the preparation of a health-promoting supplement preparation for livestock including mink, poultry and pigs. The preparation has proved suitable for the prevention against and treatment of plasmacytosis, puppy disease, enteritis virus, three-day sickness and/or “sticky” kits in mink.