Invention Grant
US07655437B2 Synthetic gene coding for human granulocyte-colony stimulating factor for the expression in E. coli
有权
编码人粒细胞集落刺激因子的合成基因，用于在大肠杆菌中表达
- Patent Title: Synthetic gene coding for human granulocyte-colony stimulating factor for the expression in E. coli
- Patent Title (中): 编码人粒细胞集落刺激因子的合成基因，用于在大肠杆菌中表达
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Application No.: US10522827Application Date: 2003-07-28
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Publication No.: US07655437B2Publication Date: 2010-02-02
- Inventor: Simona Jevsevar , Viktor Menart
- Applicant: Simona Jevsevar , Viktor Menart
- Applicant Address: SI Ljubljana
- Assignee: Lek Pharmaceuticals d.d.
- Current Assignee: Lek Pharmaceuticals d.d.
- Current Assignee Address: SI Ljubljana
- Agency: Luedeka, Neely & Graham, P.C.
- Priority: SIP-200200188 20020731
- International Application: PCT/EP03/08308 WO 20030728
- International Announcement: WO2004/013175 WO 20040212
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/11 ; C07K14/00
Abstract:
The invention relates to the synthetic gene coding for hG-CSF which enables expression in E. coli with an improved expression level of the recombinant hG-CSF regarding the total cellular proteins after expression.
Public/Granted literature
- US20060228781A1 Synthetic gene coding for human granulocyte-colony stimulating factor for the expression in e.coli Public/Granted day:2006-10-12
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