Invention Grant
- Patent Title: Method for stabilizing macrolide compounds
- Patent Title (中): 稳定大环内酯类化合物的方法
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Application No.: US10587042Application Date: 2005-01-28
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Publication No.: US07655442B2Publication Date: 2010-02-02
- Inventor: Hiroshi Ishihara , Susumu Takeda , Tomonari Yamada , Yoshiaki Asahi
- Applicant: Hiroshi Ishihara , Susumu Takeda , Tomonari Yamada , Yoshiaki Asahi
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.,Mercian Corporation
- Current Assignee: Eisai R&D Management Co., Ltd.,Mercian Corporation
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2004-020804 20040129
- International Application: PCT/JP2005/001637 WO 20050128
- International Announcement: WO2005/073223 WO 20050811
- Main IPC: C12P19/62
- IPC: C12P19/62
Abstract:
The present invention provides a method for stabilizing a macrolide compound, and an efficient method for producing the compound. Specifically, it provides a method for stabilizing a macrolide compound, in which a 12-membered ring macrolide compound, such as a compound expressed by the formula (1) and a cyclodextrin are both present, and a method for producing a macrolide compound, in which a cyclodextrin is made to be present in a culture broth of actinomycetes having an ability of producing the macrolide compound.
Public/Granted literature
- US20070155696A1 Method for stabilizing macrolide compounds Public/Granted day:2007-07-05
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