Invention Grant
- Patent Title: Nucleic acid molecules encoding endostatin protein and peptide fragments thereof
- Patent Title (中): 编码内皮抑素蛋白的核酸分子及其肽片段
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Application No.: US10232316Application Date: 2002-09-03
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Publication No.: US07655458B2Publication Date: 2010-02-02
- Inventor: Michael S. O'Reilly , M. Judah Folkman
- Applicant: Michael S. O'Reilly , M. Judah Folkman
- Applicant Address: US MA Boston
- Assignee: The Children's Medical Center Corporation
- Current Assignee: The Children's Medical Center Corporation
- Current Assignee Address: US MA Boston
- Agency: Kilpatrick Stockton LLP
- Main IPC: A61K31/317
- IPC: A61K31/317 ; C07H21/04 ; C12N15/10
Abstract:
An inhibitor of endothelial cell proliferation, capable of inhibiting angiogenesis and causing tumor regression, that is approximately 20 kDa and corresponds to a C-terminal fragment of collagen type XVIII, and methods of treating angiogenesis-related disease.
Public/Granted literature
- US20030087393A1 Therapeutic antiangiogenic compositions and methods Public/Granted day:2003-05-08
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