Invention Grant
US07655634B2 Use of hepatitis B X-interacting protein (HBXIP) in modulation of apoptosis
失效
乙型肝炎X相互作用蛋白（HBXIP）在凋亡调控中的应用
- Patent Title: Use of hepatitis B X-interacting protein (HBXIP) in modulation of apoptosis
- Patent Title (中): 乙型肝炎X相互作用蛋白（HBXIP）在凋亡调控中的应用
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Application No.: US11691393Application Date: 2007-03-26
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Publication No.: US07655634B2Publication Date: 2010-02-02
- Inventor: Ingo Tamm , John C. Reed
- Applicant: Ingo Tamm , John C. Reed
- Applicant Address: US CA La Jolla
- Assignee: The Burnham Institute
- Current Assignee: The Burnham Institute
- Current Assignee Address: US CA La Jolla
- Agency: DLA Piper LLP (US)
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/70 ; C12Q1/68 ; C12N5/00
Abstract:
Novel methods of regulating cellular apoptosis by affecting the interaction of hepatitis B X-interacting protein (HBXIP) with Survivin are described. More specifically, these novel methods of enhancing apoptosis of neoplastic cells comprises inhibiting interaction of hepatitis B X-interacting protein (HBXIP) with Survivin using siRNA or antisense compounds.
Public/Granted literature
- US20070270369A1 USE OF HEPATITIS B X-INTERACTING PROTEIN (HBXIP) IN MODULATION OF APOPTOSIS Public/Granted day:2007-11-22
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