Invention Grant
US07655651B2 Amide derivatives of 3-phenyl-dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents
失效
3-苯基 - 二氢嘧啶并[4,5-d]嘧啶酮的酰胺衍生物，其制造和用作药剂
![Amide derivatives of 3-phenyl-dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents](/docs/US/2010-02-02/US07655651B2/abs.jpg.600x600.jpg)
- Patent Title: Amide derivatives of 3-phenyl-dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents
- Patent Title (中): 3-苯基 - 二氢嘧啶并[4,5-d]嘧啶酮的酰胺衍生物，其制造和用作药剂
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Application No.: US11660198Application Date: 2005-08-30
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Publication No.: US07655651B2Publication Date: 2010-02-02
- Inventor: Richard Engh , Hubert Hertenberger , Konrad Honold , Birgit Masjost , Petra Rueger , Wolfgang Schaefer , Stefan Scheiblich , Manfred Schwaiger
- Applicant: Richard Engh , Hubert Hertenberger , Konrad Honold , Birgit Masjost , Petra Rueger , Wolfgang Schaefer , Stefan Scheiblich , Manfred Schwaiger
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Gene J. Yao
- Priority: EP04020598 20040831
- International Application: PCT/EP2005/009321 WO 20050830
- International Announcement: WO2006/024486 WO 20060309
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61K31/5355 ; C07D239/38 ; A61P29/00 ; A61P35/00 ; A61P19/08 ; A61P25/00
![Amide derivatives of 3-phenyl-dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents](/abs-image/US/2010/02/02/US07655651B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to novel amide derivatives of 3-phenyl dihydropyrimido[4,5-d]pyrimidinones, to a process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutically active agents. The present derivatives are new compounds of the general formula (I).
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