Invention Grant
US07655700B2 Transgenic mouse model and methods for treatment of neuro muscular disease by interfering with androgen-androgen receptor interaction in skeletal muscles
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转基因小鼠模型和通过干扰雄激素 - 雄激素受体在骨骼肌中的相互作用来治疗神经肌肉疾病的方法
- Patent Title: Transgenic mouse model and methods for treatment of neuro muscular disease by interfering with androgen-androgen receptor interaction in skeletal muscles
- Patent Title (中): 转基因小鼠模型和通过干扰雄激素 - 雄激素受体在骨骼肌中的相互作用来治疗神经肌肉疾病的方法
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Application No.: US11509455Application Date: 2006-08-24
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Publication No.: US07655700B2Publication Date: 2010-02-02
- Inventor: Cynthia Jordan , Douglas A. Monks , Marc Breedlove
- Applicant: Cynthia Jordan , Douglas A. Monks , Marc Breedlove
- Applicant Address: US MI East Lansing
- Assignee: Michigan State University
- Current Assignee: Michigan State University
- Current Assignee Address: US MI East Lansing
- Agency: Price, Heneveld, Cooper, DeWitt & Litton, LLP
- Main IPC: A01N37/18
- IPC: A01N37/18 ; A01N43/80 ; A01N43/56 ; C12Q1/68 ; A01K67/00 ; A01K67/027 ; C12N15/00

Abstract:
The present invention describes a transgenic mouse susceptible to neuromuscular disease. The present invention also includes methods for treatment of neuromuscular diseases by interfering with activity between androgen and androgen receptors exclusively in the muscle fibers.
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