Invention Grant
US07655735B2 Biodegradable multi-block polymeric composition capable of sol-gel transition and pharmaceutical composition comprising the same
有权
能够溶胶 - 凝胶转变的可生物降解的多嵌段聚合物组合物和包含其的药物组合物
- Patent Title: Biodegradable multi-block polymeric composition capable of sol-gel transition and pharmaceutical composition comprising the same
- Patent Title (中): 能够溶胶 - 凝胶转变的可生物降解的多嵌段聚合物组合物和包含其的药物组合物
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Application No.: US10546431Application Date: 2005-08-01
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Publication No.: US07655735B2Publication Date: 2010-02-02
- Inventor: Min-Hyo Seo , Bong-Oh Kim , Myung-Seob Shim , Sang-Jun Lee
- Applicant: Min-Hyo Seo , Bong-Oh Kim , Myung-Seob Shim , Sang-Jun Lee
- Applicant Address: KR Seoul
- Assignee: Samyang Corporation
- Current Assignee: Samyang Corporation
- Current Assignee Address: KR Seoul
- Agency: Fulbright & Jaworski LLP
- Priority: KR10-2004-0060757 20040802
- International Application: PCT/KR2005/002511 WO 20050801
- International Announcement: WO2005/014067 WO 20060902
- Main IPC: C08G63/16
- IPC: C08G63/16 ; C08G63/676 ; C08G65/332
Abstract:
The present invention relates to an ionic multi-block copolymer composition comprising tri-block copolymers having a polypropyleneoxide or polybutyleneoxide block positioned between two polyethyleneoxide blocks and the tri-block copolymers are connected through dicarboxylic acid linkages forming a multi-block copolymer having a weight average molecular weight of more than 40,000 Dalton. The higher weight average molecular weight enables the hydrolgel formed from the multi-block copolymer of the present invention to maintain its gel status for more than several days.
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