Invention Grant
US07655759B2 Recombinant bivalent monospecific immunoglobulin having at least two variable fragments of heavy chains of an immunoglobulin devoid of light chains
失效
重组二价单特异性免疫球蛋白，其具有至少两个没有轻链的免疫球蛋白重链的可变片段
- Patent Title: Recombinant bivalent monospecific immunoglobulin having at least two variable fragments of heavy chains of an immunoglobulin devoid of light chains
- Patent Title (中): 重组二价单特异性免疫球蛋白，其具有至少两个没有轻链的免疫球蛋白重链的可变片段
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Application No.: US10154971Application Date: 2002-05-28
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Publication No.: US07655759B2Publication Date: 2010-02-02
- Inventor: Raymond Hamers , Serge Muyldermans
- Applicant: Raymond Hamers , Serge Muyldermans
- Applicant Address: BE Brussels
- Assignee: Vrije Universiteit Brussel
- Current Assignee: Vrije Universiteit Brussel
- Current Assignee Address: BE Brussels
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: GB95400932.0 19950425
- Main IPC: C07K16/00
- IPC: C07K16/00
Abstract:
The present invention relates to fragments, especially variable fragments of immunoglobulins which are by nature devoid of light chains, these fragments being nevertheless capable of exhibiting a recognition and binding activity toward specific antigens. The present invention further relates to the use of such immunoglobulin fragments formed of at least one heavy chain variable fragment or derived therefrom, for therapeutic or veterinary purposes and especially for passive immunotherapy or serotherapy.
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