Invention Grant
- Patent Title: Neutralizing antibodies against GDF-8 and uses therefor
- Patent Title (中): 中和抗GDF-8的抗体并用于此
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Application No.: US11777525Application Date: 2007-07-13
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Publication No.: US07655763B2Publication Date: 2010-02-02
- Inventor: Geertruida M. Veldman , Monique V. Davies , Kening Song , Neil M. Wolfman , Kristie Grove Bridges , Anne Field , Caroline Russell , Viia Valge-Archer
- Applicant: Geertruida M. Veldman , Monique V. Davies , Kening Song , Neil M. Wolfman , Kristie Grove Bridges , Anne Field , Caroline Russell , Viia Valge-Archer
- Applicant Address: US NJ Madison GB Cambridge
- Assignee: Wyeth,MedImmune Limited
- Current Assignee: Wyeth,MedImmune Limited
- Current Assignee Address: US NJ Madison GB Cambridge
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/22 ; C07K16/24 ; C07K16/26 ; C12N15/09 ; C12N15/13 ; C12N15/63
Abstract:
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.
Public/Granted literature
- US20080044410A1 NEUTRALIZING ANTIBODIES AGAINST GDF-8 AND USES THEREFOR Public/Granted day:2008-02-21
Information query
