Invention Grant
- Patent Title: Methods and compositions for increasing antibody production
- Patent Title (中): 增加抗体产生的方法和组合物
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Application No.: US11438487Application Date: 2006-05-22
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Publication No.: US07655783B2Publication Date: 2010-02-02
- Inventor: Dorothea Reilly , Daniel Yansura
- Applicant: Dorothea Reilly , Daniel Yansura
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N5/10 ; C12P21/08
Abstract:
The invention provides methods and compositions for improved expression and production of recombinant antibodies in host cell expression systems. In particular, prokaryotic expression and production of antibodies with modified hinge cysteine residues are provided. The invention further provides compositions, kits and articles of manufacture for practicing methods of the present invention.
Public/Granted literature
- US20070128111A1 Methods and compositions for increasing antibody production Public/Granted day:2007-06-07
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