Invention Grant
US07655788B2 siRNA targeting DNA-damage-inducible transcript 4 (DDIT4)
有权
靶向DNA损伤诱导型转录物4（DDIT4）的siRNA
- Patent Title: siRNA targeting DNA-damage-inducible transcript 4 (DDIT4)
- Patent Title (中): 靶向DNA损伤诱导型转录物4（DDIT4）的siRNA
-
Application No.: US11880775Application Date: 2007-07-24
-
Publication No.: US07655788B2Publication Date: 2010-02-02
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Kalow & Springut, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A01N43/04 ; A61K31/70
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to DDIT4.
Public/Granted literature
- US20080188647A1 siRNA targeting DNA-damage-inducible transcript 4 (DDIT4) Public/Granted day:2008-08-07
Information query
