Invention Grant
US07655789B2 siRNA targeting transient receptor potential cation channel, subfamily V, member 1 (TRPV1)
有权
靶向瞬时受体潜在阳离子通道的siRNA，亚族V，成员1（TRPV1）
- Patent Title: siRNA targeting transient receptor potential cation channel, subfamily V, member 1 (TRPV1)
- Patent Title (中): 靶向瞬时受体潜在阳离子通道的siRNA，亚族V，成员1（TRPV1）
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Application No.: US11978106Application Date: 2007-10-26
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Publication No.: US07655789B2Publication Date: 2010-02-02
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Kalow & Springut, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/04
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TRPV1.
Public/Granted literature
- US20080085998A1 siRNA targeting transient receptor potential cation channel, subfamily V, member 1 (TRPV1) Public/Granted day:2008-04-10
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