Invention Grant
US07655800B2 Crystalline 1H-imidazo[4,5-b]pyridin-5-amine, 7-[5-[(cyclohexylmethylamino)-methyl]-1H-indol-2-yl]-2-methyl, sulfate (1:1), trihydrate and its pharmaceutical uses
失效
结晶的1H-咪唑并[4,5-b]吡啶-5-胺，7- [5 - [（环己基甲基氨基） - 甲基] -1H-吲哚-2-基] -2-甲基硫酸盐（1:1） 三水合物及其制药用途
![Crystalline 1H-imidazo[4,5-b]pyridin-5-amine, 7-[5-[(cyclohexylmethylamino)-methyl]-1H-indol-2-yl]-2-methyl, sulfate (1:1), trihydrate and its pharmaceutical uses](/docs/US/2010-02-02/US07655800B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline 1H-imidazo[4,5-b]pyridin-5-amine, 7-[5-[(cyclohexylmethylamino)-methyl]-1H-indol-2-yl]-2-methyl, sulfate (1:1), trihydrate and its pharmaceutical uses
- Patent Title (中): 结晶的1H-咪唑并[4,5-b]吡啶-5-胺，7- [5 - [（环己基甲基氨基） - 甲基] -1H-吲哚-2-基] -2-甲基硫酸盐（1:1） 三水合物及其制药用途
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Application No.: US11344534Application Date: 2006-02-01
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Publication No.: US07655800B2Publication Date: 2010-02-02
- Inventor: Charles E. Chase , Ikuo Kushida
- Applicant: Charles E. Chase , Ikuo Kushida
- Applicant Address: JP Tokyo
- Assignee: Eisai R & D Management Co., Ltd.
- Current Assignee: Eisai R & D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Nixon Peabody LLP
- Agent Jeffrey N. Townes
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437
![Crystalline 1H-imidazo[4,5-b]pyridin-5-amine, 7-[5-[(cyclohexylmethylamino)-methyl]-1H-indol-2-yl]-2-methyl, sulfate (1:1), trihydrate and its pharmaceutical uses](/abs-image/US/2010/02/02/US07655800B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to crystalline 1H-Imidazo[4,5-b]pyridin-5-amine, 7-[5-[(cyclohexylmethylamino)-methyl]-1H-indol-2-yl]-2-methyl, sulfate (1:1), trihydrate, E6070, its method of preparation, and its therapeutic uses. Pharmaceutical compositions containing crystalline E6070 and a pharmaceutically acceptable carrier represent one embodiment of the invention. The invention also relates to methods for treating an inflammatory disorder, an autoimmune disorder, or a proliferative disorder comprising the step of administering to a patient in need thereof a therapeutically effective amount of crystalline E6070.
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