Invention Grant
- Patent Title: Phosphine transition metal complex, method for producing the same, and antitumor agent containing the same
- Patent Title (中): 膦过渡金属络合物,其制备方法和含有它们的抗肿瘤剂
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Application No.: US12096316Application Date: 2006-11-30
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Publication No.: US07655810B2Publication Date: 2010-02-02
- Inventor: Hiroaki Kodama , Keisuke Ohto , Nobuhiko Oohara , Kazuhiro Nakatsui , Yoshirou Kaneda
- Applicant: Hiroaki Kodama , Keisuke Ohto , Nobuhiko Oohara , Kazuhiro Nakatsui , Yoshirou Kaneda
- Applicant Address: JP Tokyo
- Assignee: Nippon Chemical Industrial Co., Ltd.
- Current Assignee: Nippon Chemical Industrial Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Westerman, Hattori, Daniels & Adrian, LLP
- Priority: JP2005-352466 20051206
- International Application: PCT/JP2006/323886 WO 20061130
- International Announcement: WO2007/066557 WO 20070614
- Main IPC: A61K31/28
- IPC: A61K31/28 ; C07F15/00

Abstract:
A phosphine transition metal complex is expressed by general formula (1): wherein A represents a groups selected from among alkylene, phenylene, and cis-vinylene; M represents an atom selected from the group consisting of gold, silver, copper, and platinum; B1 and B2 each represent a substituted or unsubstituted heterocyclic group containing a trivalent phosphorus atom forming a covalent bond with A and coordinating with M; and C represents an anionic atom.
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