An air-cooled electronic component cabinet has an air sampling conduit to enable smoke detection from air from different areas within the cabinet. An air sampling conduit has one or more orifices to sample air from the different areas within the cabinet, such as adjacent different electronic chassis assemblies or enclosures stacked in a rack within the cabinet. An axial fan or blower draws air samples into the conduit, or the air samples are drawn in by operation of convection or other airflow established within the cabinet. In the air sampling conduit, the air samples are mixed and conveyed for sampling by one or more smoke detection devices mounted, e.g., within the conduit, or within an attached expansion joint section to reduce the airflow velocity or accommodate multiple smoke detection devices. Orifices in the air sampling conduit varying in size or number at different conduit areas regulate associated sampled air proportions. A variety of configurations in which such air sampling conduits are deployed are presented.