An interactive vehicle communication system, particularly for communication between motor vehicles, comprises a communication device (2) which may be placed on a stationary support (3) or a vehicle (4) traveling on a roadway and a receiver device (5), which may be placed on a stationary support (3) or a vehicle (4′) traveling on a roadway and interacts with said communication device (2). The communication device (2) comprises first means (6) for interfacing with external data detection and/or generation means, emitter means (9) for generating and emitting a visible light-emitting laser beam (8) with predetermined solid angle (a) and range, digitizing means (7) for digitizing said laser beam (8) and control means (10) for appropriately conforming and orienting said laser beam (8), to allow it to selectively interact with vehicle driving in a predetermined drive direction, excluding the other vehicles driving in the opposite drive direction. The receiver device (5) comprises: receiving means (11) for receiving said laser beam (8) and second means for interfacing (12) with external transducer means.