A fire safety system includes a sensor arrangement and control scheme for quickly sensing a fire, accurately identifying its location, and controlling a set of ceiling fans and overhead sprinklers to efficiently extinguish the fire. The fire safety system is particularly suited for large buildings such as warehouses, factories, gymnasiums, retail stores, auditoriums, convention centers, theaters or other buildings with large open areas. In some examples, the overhead fans are disabled prior to activating the sprinklers. The placement of the fire sensors, in some cases, are selected upon first considering the location of the overhead fans.