A bone cement mixing and delivery system is provided in which separate components of bone cement are mixed together in a mixer to form a bone cement mixture. The mixer includes a mixing paddle and a mixing shaft connected to the mixing paddle. A motor operatively engages the mixing shaft to rotate the mixing shaft and the mixing paddle to mix the components in a mixing chamber. The motor also operatively engages a transfer mechanism. After a predetermined mixing period has elapsed, the motor automatically actuates the transfer mechanism to transfer the mixture to a delivery device. The mixture is then delivered to a target site, such as a vertebral body of a patient or other anatomical site.