Certain embodiments provide systems and methods for gantry support. Certain embodiments provide a mobile imaging system. The system includes a base and a gantry member moveably attached to the base. The gantry member includes an imaging source. The system also includes a gantry support positioned on the base for supporting the gantry member. The gantry support contacts the gantry member at one or more points in a range of motion for the gantry member. Certain embodiments provide a method for gantry member stabilization. The method includes providing a gantry support on a gantry base to provide support for an imaging system gantry member. The imaging system gantry member is attached to the gantry base. The method further includes positioning the gantry support with respect to the gantry member to support the gantry member along at least a portion of a path of movement of the gantry member.