Invention Grant
- Patent Title: Detecting a bacterial process in chronic rhinosinusitis
- Patent Title (中): 检测慢性鼻鼻窦炎中的细菌过程
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Application No.: US11897494Application Date: 2007-08-30
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Publication No.: US07659080B2Publication Date: 2010-02-09
- Inventor: Jens Ponikau , David Sherris , Hirohito Kita
- Applicant: Jens Ponikau , David Sherris , Hirohito Kita
- Applicant Address: US NY Amherst US MN Rochester
- Assignee: The Research Foundation of State University of New York,Mayo Foundation For Medical Education and Research
- Current Assignee: The Research Foundation of State University of New York,Mayo Foundation For Medical Education and Research
- Current Assignee Address: US NY Amherst US MN Rochester
- Agency: Hodgson Russ LLP
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/567 ; G01N33/00 ; G01N33/573 ; C12N9/66
Abstract:
The present invention provides a method for identifying bacterial induced rhinosinusitis. The method comprises obtaining a nasal or paranasal mucus sample and detecting the presence of neutrophil degranulation in the mucus sample. Degranulation of neutrophils can be determined by morphological analysis of the cells in the mucus or by detection of released (i.e., “free”) granule content markers such as neutrophil elastase or myeloperoxidase. Based on an accurate determination of the cause of sinusitis as described herein, an appropriate treatment can be instituted.
Public/Granted literature
- US20080090252A1 Detecting a bacterial process in chronic rhinosinusitis Public/Granted day:2008-04-17
Information query
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