Invention Grant
US07659084B2 Methods for detecting and isolating antigen-specific T lymphocytes with CD40/C154 inhibitors
失效
用CD40 / C154抑制剂检测和分离抗原特异性T淋巴细胞的方法
- Patent Title: Methods for detecting and isolating antigen-specific T lymphocytes with CD40/C154 inhibitors
- Patent Title (中): 用CD40 / C154抑制剂检测和分离抗原特异性T淋巴细胞的方法
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Application No.: US10525238Application Date: 2003-08-22
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Publication No.: US07659084B2Publication Date: 2010-02-09
- Inventor: Marco Frentsch , Martin Rothe , Andreas Thiel
- Applicant: Marco Frentsch , Martin Rothe , Andreas Thiel
- Applicant Address: DE Bergisch Gladbach
- Assignee: Miltenyi Biotec GmbH
- Current Assignee: Miltenyi Biotec GmbH
- Current Assignee Address: DE Bergisch Gladbach
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: EP02090300 20020823
- International Application: PCT/EP03/09354 WO 20030822
- International Announcement: WO2004/027428 WO 20040401
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C12N5/08
Abstract:
What is suggested herein is the use of CD154 for the detection and/or isolation of antigen-specific T lymphocytes and a method for the detection and/or isolation of antigen-specific T lymphocytes, wherein the suspension is contacted with a CD40/CD154 system inhibitor, intra- or extracellular determination of CD154 is effected, and the cells having CD154 are detected and/or isolated.
Public/Granted literature
- US20060121027A1 Method for detecting and isolating t lymphocytes that recognize a defined antigen Public/Granted day:2006-06-08
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