Invention Grant
US07659120B2 Δ 15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
有权
适用于改变含油植物和酵母中多不饱和脂肪酸水平的Delta 15去饱和酶
- Patent Title: Δ 15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
- Patent Title (中): 适用于改变含油植物和酵母中多不饱和脂肪酸水平的Delta 15去饱和酶
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Application No.: US10985254Application Date: 2004-11-10
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Publication No.: US07659120B2Publication Date: 2010-02-09
- Inventor: Narendra S. Yadav , Hongxiang Zhang
- Applicant: Narendra S. Yadav , Hongxiang Zhang
- Applicant Address: US DE Wilmington
- Assignee: E. I. du Pont de Nemours and Company
- Current Assignee: E. I. du Pont de Nemours and Company
- Current Assignee Address: US DE Wilmington
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C07H21/04 ; C12N1/20
Abstract:
The present invention relates to fungal Δ-15 fatty acid desaturases that are able to catalyze the conversion of linoleic acid (18:2, LA) to alpha-linolenic acid (18:3, ALA). Nucleic acid sequences encoding the desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising the desaturase genes, and recombinant host plants and microorganisms expressing increased levels of the desaturases are described. Methods of increasing production of specific omega-3 and omega-6 fatty acids by over-expression of the Δ-15 fatty acid desaturases are also described herein.
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